Medical School

Global Pediatrics

Department of Pediatrics

Chandy John, M.D., M.S.

MEDPEDS2 - Image - 180x222 - Chandy John

Academic Title

Professor of Pediatrics and Medicine


Medical School
University of Michigan; Ann Arbor, MI
Internal Medicine and Pediatrics Residency; University of Michigan; Ann Arbor, MI
Pediatric Infectious Diseases Fellowship; Rainbow Babies & Children's Hospital and Case Western Reserve University; Cleveland, OH
Integrated Pre-medical/Medical School Program; University of Michigan; Ann Arbor, MI
Epidemiology; Case Western Reserve University School of Graduate Studies; Cleveland, OH

Contact Info


612 625 8383

612 625 2929

Administrative Contact

612 625 8383

Office Address

717 Delaware St SE, Room 362
Minneapolis, MN  55414

Mailing Address

717 Delaware St SE, Mail Code 1932
Minneapolis, MN 55414


Bio Statement

Chandy John, MD, MS, holds the Marguerite and James Dugger Endowed Professorship in Pediatrics at the University of Minnesota. He is Professor of Pediatrics and Medicine, Director of the Division of Global Pediatrics, and a member of the Division of Pediatric Infectious Diseases at the University of Minnesota. Dr. John was a faculty member at Case Western Reserve University from 1998-2005. He joined the University of Minnesota in 2005, and established the Division of Global Pediatrics, the first division of Pediatrics devoted to global child health in the USA. Dr. John also guided development of the University of Minnesota's pediatric global health track for pediatric and medicine-pediatrics residents.

Dr. John has served as an appointed member of the Clinical Research and Field Studies study section of the National Institutes of Health, and has served on numerous other NIH review committees, as well as review committees for the Gates Foundation, Wellcome Trust, Thrasher Foundation, French National Research Agency and other national and international research institutions. He has served on national committees for the American Society of Tropical Medicine and Hygiene, the American Pediatric Society, the Society for Pediatric Research, and the Pediatric Infectious Diseases Society.

His published writing outside of medical research includes essays, poetry, and short stories.

Research Interests

Dr. John conducts research studies in malaria immunoepidemiology and pathogenesis, the long-term neurodevelopmental sequelae of infectious diseases, and the interactions between infection, nutrition and child neurodevelopment. He has had NIH-funded research studies and/or training grants in Kenya since 1999 and in Uganda since 2003, and has published over 90 peer-reviewed research publications and 22 book chapters.


Research Projects


Current Projects


NIH/NINDS 2R01 NS055346-06 (PI: John, CC) 01/15/2014 – 12/31/2018 Neurodevelopmental outcomes in children with severe malaria
Doris Duke Innovations in Clinical Research Award #2013139 (PI: John, CC) 09/01/2013 – 8/31/2016 Novel Use of Hydroxyurea in an African Region with Malaria (NOHARM)
Doris Duke International Clinical Research Fellowships Training Grant (PI: John, CC) 09/01/2012 – 08/31/2017
NIH/FIC R25TW009345 (Co-PIs: John CC, Zunt, J, Kolars, J, Nerurkar, V) 4/13/12-2/28/17
Northern and Pacific Universities Global Health Research Training consortium
NIH/NICHD 1R01HD064416-01 (PI: Boivin, MJ)
Computerized cognitive rehabilitation in children after severe malaria
Role: Co-investigator

NIH/NINDS/FIC 1D43NS078280-01 (PI: John, CC)
Research training in infection and neurodevelopment in Uganda
NIH/NICHD U01 HD064698-01 (PI: John, CC)
Acute vs. delayed iron therapy: effect on iron status, anemia and cognition
NIH/FIC D43 TW0080085 (PI: John, CC)
Translational research in malaria transmission and immunity in Kenya

Completed Projects

NIH/NINDS R01 NS055349 (PI: John, CC)
 Pathogenesis of cognitive/neurologic deficits in central nervous system malaria
UHN, Toronto (PI: Kain, KC; Co-PI: John, CC)
Inhaled nitric oxide for the adjunctive therapy of severe malaria: a randomized controlled trial
University of Minnesota Amplatz Award (PI: John, CC)
How does reduction of malaria transmission affect immune responses to Plasmodium falciparum and prevalence of anemia?


Leadership Roles

Director, Division of Global Pediatrics, University of Minnesota Medical School; Minneapolis, MN; 2005-present

Co-Director, Rainbow Center for International Child Health, Rainbow Babies & Children’s Hospital; Cleveland, OH; 2001-2005



Bailey K. Ashford Medal, American Society for Tropical Medicine and Hygiene, 2011
Amplatz Scholar Award, University of Minnesota Department of Pediatrics, 2010
Emerging Physician Leadership Program, University of Minnesota Medical School, 2008-2011
Outstanding Faculty Educator, University of Minnesota, Department of Pediatrics, 2007
Outstanding Contribution to Resident Education, Rainbow Babies & Children’s Hospital, 2005
Best Contribution Award for Teaching Excellence, Case Western Reserve University, 2004
Young Investigator Award, Pediatric Infectious Disease Society, 2004
Glennan Teaching Scholar Award, Case Western Reserve University, 2002
AMSA International Health Fellowship, Ilorin, Nigeria, 1989



Out of more than 85 peer-reviewed publications; see full listing on PubMed

Hawkes M, Conroy AL, Opoka RO, Namasopo S, Liles WC, John CC, Kain KC. Performance of Point-of-Care Diagnostics for Glucose, Lactate, and Hemoglobin in the Management of Severe Malaria in a Resource-Constrained Hospital in Uganda. Am J Trop Med Hyg. 2014 Mar 3. [Epub ahead of print].

Hawkes M, Conroy AL, Opoka RO, Namasopo S, Liles WC, John CC, Kain KC. Use of a three-band HRP2/pLDH combination rapid diagnostic test increases diagnostic specificity for falciparum malaria in Ugandan children. Malar J. 2014 Feb 1;13:43. PMCID: PMC3922073.

Raabe VN, Sautter C, Chesney M, Eckerle JK, Howard CR, John CC. Hepatitis A Screening for Internationally Adopted Children From Hepatitis A Endemic Countries. Clin Pediatr (Phila). 2013 Oct 17. PMID: 24137028.

John CC. Complex Interactions of HIV Infection, Malaria, and Iron Deficiency. Clin Infect Dis. 2013 Dec; 57(11):1635-7. PMID: 23956166. PMCID: pending.

Ochola LA, Ng'wena GM, Noland GS, Ondigo BN, Ayodo G, John CC. The Plasmodium falciparum Antigen MB2 Induces Interferon-γ and Interleukin-10 Responses in Adults in Malaria Endemic Areas of Western Kenya. J Glob Infect Dis. 2013 Oct;5(4):131-7. PMCID: pending

Ayieko C, Maue AC, Jura WG, Noland GS, Ayodo G, Rochford R, John CC. Changes in B Cell Populations and Merozoite Surface Protein-1-Specific Memory B Cell Responses after Prolonged Absence of Detectable P. falciparum Infection. PLoS One. 2013 Jun 27;8(6):e67230. Print 2013. PMCID: PMC3695086.

Moormann AM, Sumba PO, Chelimo K, Fang H, Tisch DJ, Dent AE, John CC, Long CA, Vulule J, Kazura JW. Humoral and cellular immunity to Plasmodium falciparum merozoite surface protein 1 and protection from infection with blood-stage parasites. J Infect Dis. 2013 Jul;208(1):149-58. PMCID: PMC3666139.

Eckerle JK, Howard CR, John CC. Infections in internationally adopted children. Pediatr Clin North Am. 2013 Apr;60(2):487-505.

Bangirana P, Menk J, John CC, Boivin MJ, Hodges JS. The association between cognition and academic performance in Ugandan children surviving malaria with neurological involvement. PLOS One 2013; 8(2): e55653. PMCID: PMC3562187


Chandy John Lab

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  • Last modified on April 11, 2014